Oh my goodness, let me tell you about my Chicken Tzatziki Casserole! It’s one of those dishes that just makes your taste buds dance! The creamy, tangy tzatziki sauce perfectly complements the tender chicken, and when you add in the fresh spinach and feta, wow—it’s a flavor explosion! Not only is it delicious, but it’s also packed with nutrients, making it a fantastic choice for anyone looking to eat healthy. Plus, it’s super easy to whip up, fitting seamlessly into a busy weeknight routine. Trust me, you’re going to want to make this Mediterranean delight again and again!

Ingredients List
Gather these simple ingredients to create your Chicken Tzatziki Casserole. It’s all about fresh flavors and easy prep!
- 2 cups cooked chicken, shredded (leftover rotisserie chicken works great!)
- 1 cup tzatziki sauce (store-bought or homemade, just make sure it’s creamy and tangy)
- 1 cup cooked rice (I love using brown rice for a nutty flavor)
- 1 cup spinach, chopped (fresh is best, but frozen works in a pinch)
- 1 cup feta cheese, crumbled (the saltiness of feta really elevates this dish)
- 1 teaspoon garlic powder (for that extra kick!)
- 1 teaspoon dried dill (to bring in that classic Mediterranean flavor)
- Salt and pepper to taste (don’t be shy, season it to your liking!)
How to Prepare Chicken Tzatziki Casserole
Alright, let’s get cooking! First things first, preheat your oven to 350°F (175°C). This is super important because you want everything to be nice and hot when it goes in. While that’s heating up, grab a large bowl and toss in your shredded chicken, tzatziki sauce, cooked rice, chopped spinach, garlic powder, dill, and a sprinkle of salt and pepper. Give it a good mix! You want everything to be well combined and coated in that delicious sauce.
Now, once your mixture looks all pretty and uniform, transfer it into a greased baking dish. I usually use a 9×13 inch dish, but you can adjust depending on what you have. Spread it out evenly so that it bakes uniformly. The last step before baking? Crumble that feta cheese on top! Seriously, it’s what makes this casserole sing.
Pop it in the oven and set your timer for 25-30 minutes. You’ll know it’s done when the cheese is slightly golden and everything is bubbly. Take it out and let it cool for a few minutes before diving in. Trust me, the aroma will be irresistible!
Why You’ll Love This Recipe
- Quick to Prepare: In just 15 minutes of prep, you’ll have a delicious casserole ready to go in the oven.
- Packed with Flavor: The combination of tangy tzatziki, savory chicken, and creamy feta creates a taste sensation that’s hard to resist!
- Healthy Dish: With lean protein, fresh veggies, and wholesome ingredients, this casserole is a guilt-free delight.
- Perfect for Meal Prep: It’s easy to make ahead, making it a great option for busy weeknights or meal prepping for the week.
- Family-Friendly: Even picky eaters will love this dish—it’s comfort food with a Mediterranean twist!
Tips for Success
To make your Chicken Tzatziki Casserole turn out perfectly, here are a few of my favorite tips! First, if you don’t have tzatziki on hand, you can easily swap it for Greek yogurt mixed with a little cucumber, garlic, and lemon juice for that fresh taste. Also, using leftover chicken is a game changer—just shred it and you’re ready to go! Make sure to grease your baking dish well to prevent sticking. And don’t rush the cooling time after it comes out of the oven; letting it sit for a few minutes helps everything settle and makes serving easier!
Nutritional Information
Now, I know many of you are curious about the nutritional breakdown of this delicious Chicken Tzatziki Casserole, so here are the estimated values per serving! Each generous portion contains about 320 calories, which is great for a filling meal. You’ll also get around 10 grams of fat, with 4 grams being saturated fat. It’s a protein powerhouse, packing in approximately 25 grams of protein to keep you satisfied. On the carb side, expect about 36 grams, along with a couple of grams of fiber and just 3 grams of sugar. Remember, these values are estimates, but they give you a good idea of how wholesome this dish is!
FAQ Section
Got questions about my Chicken Tzatziki Casserole? I’ve got answers! First up, Can I use other proteins? Absolutely! This recipe works great with turkey or even chickpeas for a vegetarian twist. What if I don’t have tzatziki sauce? No worries! Greek yogurt mixed with diced cucumbers, garlic, and a splash of lemon juice can be a perfect substitute. Can I freeze leftovers? Yes, it freezes beautifully! Just make sure to store it in an airtight container. And finally, How long will it last in the fridge? You can enjoy it for up to 3 days, but trust me, it’s so good, it won’t last that long!
Storage & Reheating Instructions
Storing leftovers of your Chicken Tzatziki Casserole is super easy! Just let it cool completely, then transfer any uneaten portions to an airtight container. It’ll keep in the fridge for about 3 days, so you can enjoy those tasty flavors again soon! If you want to keep it longer, you can freeze it for up to 2 months. Just be sure to wrap it tightly in plastic wrap or use a freezer-safe container to prevent freezer burn.
When it’s time to reheat, simply thaw it overnight in the fridge if frozen, then pop it in the oven at 350°F (175°C) for about 20 minutes, or until it’s heated through. You can also microwave individual servings for a quick fix! Just cover it with a damp paper towel to keep it moist.
Serving Suggestions
Now that your Chicken Tzatziki Casserole is ready to go, let’s talk about what to serve alongside it! I love pairing this dish with a simple Greek salad—just some fresh cucumbers, juicy tomatoes, red onion, and olives drizzled with olive oil and lemon juice. It adds a nice crunch and complements the creamy casserole perfectly! You could also serve it with warm pita bread for that delightful Mediterranean vibe. And don’t forget about roasted vegetables! A mix of zucchini, bell peppers, and eggplant tossed in olive oil and herbs makes a colorful, tasty side. Enjoy these combos for a well-rounded meal that’s sure to impress!
For more delicious recipes, check out our all recipes page!
Learn more about the health benefits of tzatziki sauce and how it can enhance your meals!
Print
Chicken Tzatziki Casserole: 5 Quick & Tasty Steps
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Total Time: 45 minutes
- Yield: 4 servings 1x
- Category: Main Dish
- Method: Baking
- Cuisine: Mediterranean
- Diet: Low Fat
Description
A flavorful and healthy casserole combining chicken and tzatziki sauce.
Ingredients
- 2 cups cooked chicken, shredded
- 1 cup tzatziki sauce
- 1 cup cooked rice
- 1 cup spinach, chopped
- 1 cup feta cheese, crumbled
- 1 teaspoon garlic powder
- 1 teaspoon dried dill
- Salt and pepper to taste
Instructions
- Preheat the oven to 350°F (175°C).
- In a large bowl, combine the shredded chicken, tzatziki sauce, cooked rice, spinach, garlic powder, dill, salt, and pepper.
- Transfer the mixture to a greased baking dish.
- Top with crumbled feta cheese.
- Bake for 25-30 minutes until heated through and the cheese is slightly golden.
- Let cool for a few minutes before serving.
Notes
- Substitute Greek yogurt for tzatziki for a lighter option.
- Can be made ahead and refrigerated.
- Use leftover chicken for quicker preparation.
Nutrition
- Serving Size: 1 serving
- Calories: 320
- Sugar: 3g
- Sodium: 600mg
- Fat: 10g
- Saturated Fat: 4g
- Unsaturated Fat: 6g
- Trans Fat: 0g
- Carbohydrates: 36g
- Fiber: 2g
- Protein: 25g
- Cholesterol: 70mg
Keywords: Chicken Tzatziki Casserole, casserole recipes, Mediterranean chicken